HitPredict

Interactor 1: PTN13 (Q12923)
Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1)
Gene: PTPN13

Interactor 2: RPGF2 (Q9Y4G8)
Rap guanine nucleotide exchange factor 2 (Cyclic nucleotide ras GEF) (CNrasGEF) (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF-1) (Ras/Rap1-associating GEF-1)
Gene: RAPGEF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	25332235
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~RA, PDZ~PDZ
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 2485 Hs			1 1499
+	Hs
		1020197 PTN13_HUMAN (1-2485): 0: 1895: 100.00		RPGF6_HUMAN (20-1499): 0: 1352: 63.43
+	Hs
		1020161 PTN13_HUMAN (1-2485): 0: 1895: 100.00		RPGF1_HUMAN (497-962): 7.1e-99: 345: 19.96
+	Hs
		1020189 PTN13_HUMAN (1-2485): 0: 1895: 100.00		RGPS2_HUMAN (700-1105): 3.12e-81: 281: 19.76
+	Hs
		1336377 E41L5_HUMAN (513-1220): 6.79e-115: 385: 16.35		RPGF2_HUMAN (1-1499): 0: 1710: 100.00
+	Hs
		1199794 MAGI2_HUMAN (873-1270): 1.19e-11: 72.9: 16.50		RPGF2_HUMAN (1-1499): 0: 1710: 100.00
+	Hs
		719460 MERL_HUMAN (558-1049): 1.41e-117: 388: 23.65		SOS1_HUMAN (464-1176): 1.68e-98: 348: 13.86
+	Hs
		985942 PTN11_HUMAN (2083-2480): 4.2e-117: 387: 31.47		SOS1_HUMAN (464-1176): 1.68e-98: 348: 13.86
+	Mm
		420377 PTPRC_MOUSE (2199-2468): 6.69e-67: 252: 26.23		SOS1_MOUSE (464-1176): 2.43e-98: 348: 14.49
+	Hs
		665875 PTN6_HUMAN (2215-2480): 9.54e-47: 181: 40.48		SOS1_HUMAN (464-1176): 1.68e-98: 348: 13.86