HitPredict

Interactor 1: ELAV2 (Q12926)
ELAV-like protein 2 (ELAV-like neuronal protein 1) (Hu-antigen B) (HuB) (Nervous system-specific RNA-binding protein Hel-N1)
Gene: ELAVL2

Interactor 2: PSPC1 (Q8WXF1)
Paraspeckle component 1 (Paraspeckle protein 1)
Gene: PSPC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	NOPS~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 359 Hs			1 523
+	Hs
		516484 ELAV2_HUMAN (1-359): 5.95e-103: 309: 100.00		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		1020306 ELAV2_HUMAN (1-359): 5.95e-103: 309: 100.00		PABP5_HUMAN (86-416): 1.38e-52: 184: 16.90
+	Hs
		1055876 ELAV3_HUMAN (1-359): 4.18e-92: 281: 76.02		PABP5_HUMAN (86-416): 1.38e-52: 184: 16.90
+	Hs
		1031404 PABP4_HUMAN (4-282): 1.19e-46: 169: 19.87		PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00
+	Hs
		1020249 ELAV2_HUMAN (1-359): 5.95e-103: 309: 100.00		PABP4_HUMAN (3-149): 2.52e-27: 118: 18.83
+	Hs
		474019 ELAV2_HUMAN (1-359): 5.95e-103: 309: 100.00		PAB4L_HUMAN (147-425): 7.96e-26: 110: 13.89
+	Hs
		516495 PABP4_HUMAN (4-282): 1.19e-46: 169: 19.87		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		1020265 ELAV2_HUMAN (1-359): 5.95e-103: 309: 100.00		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		1020259 ELAV2_HUMAN (1-359): 5.95e-103: 309: 100.00		ELAV3_HUMAN (84-151): 6.6e-13: 72.2: 32.43
+	Xl
		1265032 ELAV2_XENLA (1-359): 2.27e-96: 293: 91.16		ELAV2_XENLA (84-156): 4.64e-13: 72.6: 31.65
+	Dm
		114303 M9PBZ2_DROME (34-358): 2.38e-83: 268: 59.88		Q9VYI0_DROME (10-157): 7.3e-15: 78: 24.52
+	Dm
		114290 M9PBZ2_DROME (34-358): 2.38e-83: 268: 59.88		M9PBZ2_DROME (84-157): 1.35e-13: 75.3: 31.25
+	Dm
		114292 M9PBZ2_DROME (34-358): 2.38e-83: 268: 59.88		ELAV_DROME (84-157): 1.77e-12: 71.4: 27.50
+	Dm
		562818 ELAV_DROME (17-357): 9.08e-75: 240: 50.14		Q9VYI0_DROME (10-157): 7.3e-15: 78: 24.52
+	Dm
		562814 ELAV_DROME (17-357): 9.08e-75: 240: 50.14		ELAV_DROME (84-157): 1.77e-12: 71.4: 27.50
+	Hs
		474021 PABP4_HUMAN (4-282): 1.19e-46: 169: 19.87		PAB4L_HUMAN (147-425): 7.96e-26: 110: 13.89
+	Hs
		1031344 PABP4_HUMAN (4-282): 1.19e-46: 169: 19.87		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11