HitPredict

Interactor 1: EPS8 (Q12929)
Epidermal growth factor receptor kinase substrate 8
Gene: EPS8

Interactor 2: STF1 (Q13285)
Steroidogenic factor 1 (SF-1) (STF-1) (hSF-1) (Adrenal 4-binding protein) (Fushi tarazu factor homolog 1) (Nuclear receptor subfamily 5 group A member 1) (Steroid hormone receptor Ad4BP)
Gene: NR5A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	unassigned3713
Identification Methods	phage display
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 822 Hs			1 461
+	Hs
		369501 EPS8_HUMAN (1-822): 0: 994: 100.00		ESR1_HUMAN (13-154): 2.14e-39: 151: 34.90
+	Dm
		1259326 Q95TJ6_DROME (62-807): 0: 600: 24.58		Q8WS79_DROME (4-95): 6.75e-30: 123: 56.52
+	Dm
		1279634 Q95TJ6_DROME (62-807): 0: 600: 24.58		Q9VSE9_DROME (4-95): 6.71e-30: 123: 56.52
+	Hs
		412175 FYN_HUMAN (454-613): 1.08e-27: 120: 16.57		STF1_HUMAN (1-461): 1.69e-126: 376: 100.00
+	Hs
		802586 CRK_HUMAN (487-661): 8.43e-28: 116: 18.75		STF1_HUMAN (1-461): 1.69e-126: 376: 100.00
+	Hs
		823920 BTK_HUMAN (422-701): 8.99e-28: 121: 10.77		NR2C2_HUMAN (11-457): 1.94e-116: 355: 21.80
+	Hs
		557679 NCK1_HUMAN (536-621): 1.03e-18: 90.8: 30.23		STF1_HUMAN (1-461): 1.69e-126: 376: 100.00
+	Hs
		209047 NCK2_HUMAN (535-612): 1.02e-12: 72.7: 24.69		STF1_HUMAN (1-461): 1.69e-126: 376: 100.00
+	Hs
		207771 PPIP1_HUMAN (423-588): 1.18e-29: 124: 18.56		RXRB_HUMAN (11-93): 9.37e-44: 163: 51.81
+	Hs
		368834 YES_HUMAN (448-612): 4.43e-29: 124: 16.00		ESR1_HUMAN (13-154): 2.14e-39: 151: 34.90