HitPredict

Interactor 1: TRAP1 (Q12931)
Heat shock protein 75 kDa, mitochondrial (HSP 75) (Heat shock protein family C member 5) (TNFR-associated protein 1) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1)
Gene: TRAP1

Interactor 2: PINK1 (Q9BXM7)
Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)
Gene: PINK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.819

The method score is based on:

Property Details
Experiments 31300519, 17579517
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, protein kinase assay
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HSP90~Pkinase
Common GO terms GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005758 - mitochondrial intermembrane space
GO:0016020 - membrane
and 1 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 704
Hs

1 581
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Last updated: 15 Jul 2024