Interactor 1: TRAF2 (Q12933)
TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3)
Gene: TRAF2
Interactor 2: TRADD (Q15628)
Tumor necrosis factor receptor type 1-associated DEATH domain protein (TNFR1-associated DEATH domain protein) (TNFRSF1A-associated via death domain)
Gene: TRADD
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 0.60 | 0.766 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27768232, 30561431, 8702708, 11479302, 8565075, 19815541, 11181075, 14743216, 23429285, 32296183, 10892748, 10911999, 32968279, 9020361, 12796506, 23955153, 18439848, unassigned1304 |
| Identification Methods | affinity chromatography technology, two hybrid, x-ray crystallography, pull down, tandem affinity purification, anti tag coimmunoprecipitation, virotrap, two hybrid prey pooling approach, two hybrid array, validated two hybrid and 1 others
more... |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0002947 - tumor necrosis factor receptor superfamily complex GO:0005164 - tumor necrosis factor receptor binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction and 6 others more... |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
