HitPredict

Interactor 1: TRAF2 (Q12933)
TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3)
Gene: TRAF2

Interactor 2: UB2V2 (Q15819)
Ubiquitin-conjugating enzyme E2 variant 2 (DDVit 1) (Enterocyte differentiation-associated factor 1) (EDAF-1) (Enterocyte differentiation-promoting factor 1) (EDPF-1) (MMS2 homolog) (Vitamin D3-inducible protein)
Gene: UBE2V2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	20047764
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0070534 - protein K63-linked ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 501 Hs			1 145
+	Hs
		849315 TRAF2_HUMAN (1-501): 2.31e-159: 463: 100.00		UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82
+	Hs
		919713 TRAF2_HUMAN (1-501): 2.31e-159: 463: 100.00		UB2D2_HUMAN (10-144): 3.07e-58: 179: 22.06
+	Mm
		761806 TRAF2_MOUSE (1-501): 9.33e-158: 459: 86.83		UB2D3_MOUSE (10-144): 9.91e-58: 178: 22.06
+	Hs
		1020640 TRAF2_HUMAN (1-501): 2.31e-159: 463: 100.00		UB2V1_HUMAN (3-145): 3.5e-55: 171: 89.51
+	Hs
		930181 TRAF2_HUMAN (1-501): 2.31e-159: 463: 100.00		UBC9_HUMAN (7-143): 1.02e-54: 170: 21.01
+	Hs
		849318 TRAF3_HUMAN (14-501): 2.21e-112: 345: 31.31		UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82
+	Hs
		1377466 TRAF6_HUMAN (2-498): 5.24e-109: 335: 27.08		UB2D4_HUMAN (10-144): 9.98e-60: 183: 24.27
+	Hs
		849496 TRAF6_HUMAN (2-498): 5.24e-109: 335: 27.08		UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82
+	Mm
		895974 TRAF6_MOUSE (2-498): 2.51e-110: 339: 27.87		UB2D3_MOUSE (10-144): 9.91e-58: 178: 22.06
+	Hs
		930185 TRAF3_HUMAN (14-501): 2.21e-112: 345: 31.31		UBC9_HUMAN (7-143): 1.02e-54: 170: 21.01
+	Hs
		919916 TRAF6_HUMAN (2-498): 5.24e-109: 335: 27.08		UB2D2_HUMAN (10-144): 3.07e-58: 179: 22.06
+	Hs
		1079029 TRAF6_HUMAN (2-498): 5.24e-109: 335: 27.08		UB2V2_HUMAN (1-145): 4.36e-58: 178: 100.00
+	Hs
		895966 TRAF6_HUMAN (2-498): 5.24e-109: 335: 27.08		UB2D3_HUMAN (10-144): 9.91e-58: 178: 22.06
+	Hs
		851912 TRAF6_HUMAN (2-498): 5.24e-109: 335: 27.08		UB2E1_HUMAN (1-143): 2.16e-56: 176: 22.92
+	Hs
		1033153 TRAF6_HUMAN (2-498): 5.24e-109: 335: 27.08		UB2V1_HUMAN (3-145): 3.5e-55: 171: 89.51
+	Hs
		930472 TRAF6_HUMAN (2-498): 5.24e-109: 335: 27.08		UBC9_HUMAN (7-143): 1.02e-54: 170: 21.01
+	Hs
		849427 TRAF4_HUMAN (17-498): 1.52e-94: 296: 29.12		UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82
+	Hs
		930374 TRAF4_HUMAN (17-498): 1.52e-94: 296: 29.12		UBC9_HUMAN (7-143): 1.02e-54: 170: 21.01
+	Mm
		1122651 RO52_MOUSE (17-369): 1.05e-57: 200: 14.53		Q569Y6_MOUSE (3-145): 3.03e-58: 179: 85.32
+	Hs
		584907 RO52_HUMAN (28-368): 2.44e-56: 196: 12.68		UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82