HitPredict

Interactor 1: TRAF2 (Q12933)
TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3)
Gene: TRAF2

Interactor 2: TNR14 (Q92956)
Tumor necrosis factor receptor superfamily member 14 (Herpes virus entry mediator A) (Herpesvirus entry mediator A) (HveA) (Tumor necrosis factor receptor-like 2) (TR2) (CD antigen CD270)
Gene: TNFRSF14

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.719

The method score is based on:

Property Details
Experiments 9153189, 9162022, 10799510, 19332782, 17353931
Identification Methods two hybrid, affinity chromatography technology, pull down, anti bait coimmunoprecipitation, coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0031625 - ubiquitin protein ligase binding
GO:0045087 - innate immune response
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 501
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024