HitPredict

Interactor 1: TRAF2 (Q12933)
TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3)
Gene: TRAF2

Interactor 2: TNR12 (Q9NP84)
Tumor necrosis factor receptor superfamily member 12A (Fibroblast growth factor-inducible immediate-early response protein 14) (FGF-inducible 14) (Tweak-receptor) (TweakR) (CD antigen CD266)
Gene: TNFRSF12A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.651

Property	Details
Experiments	30373932, 11728344, 21525013
Identification Methods	affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:2001238 - positive regulation of extrinsic apoptotic signaling pathway
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 501 Hs			1 129
+	Hs
		1023806 TRAF1_HUMAN (130-499): 1.15e-88: 279: 37.44		TNR12_HUMAN (1-129): 1.02e-75: 222: 100.00