HitPredict

Interactor 1: TRAF2 (Q12933)
TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3)
Gene: TRAF2

Interactor 2: PDLI7 (Q9NR12)
PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma)
Gene: PDLIM7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	21864338
Identification Methods	protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 501 Hs			1 457
+	Hs
		1024767 TRAF3_HUMAN (14-501): 2.21e-112: 345: 31.31		PDLI7_HUMAN (1-457): 2.02e-91: 286: 100.00
+	Hs
		1344060 TRAF6_HUMAN (2-498): 5.24e-109: 335: 27.08		PDLI7_HUMAN (1-457): 2.02e-91: 286: 100.00
+	Hs
		549155 TRAF2_HUMAN (1-501): 2.31e-159: 463: 100.00		ZN250_HUMAN (362-457): 4.28e-23: 103: 6.25
+	Mm
		250817 TRAF2_MOUSE (1-501): 9.33e-158: 459: 86.83		FHL2_MOUSE (304-449): 1.31e-15: 79: 29.05
+	Hs
		532309 TRAF2_HUMAN (1-501): 2.31e-159: 463: 100.00		ZNF35_HUMAN (73-274): 7.41e-12: 69.2: 3.83
+	Hs
		1355159 TRAF6_HUMAN (2-498): 5.24e-109: 335: 27.08		LIMD1_HUMAN (78-457): 6.82e-53: 190: 17.84
+	Hs
		1020675 TRAF2_HUMAN (1-501): 2.31e-159: 463: 100.00		TRIP6_HUMAN (396-457): 6.89e-09: 59.7: 27.42
+	Hs
		1294462 TRAF6_HUMAN (2-498): 5.24e-109: 335: 27.08		AJUBA_HUMAN (115-457): 1.26e-52: 187: 17.04
+	Mm
		936266 TRAF6_MOUSE (2-498): 2.51e-110: 339: 27.87		PAXI_MOUSE (61-396): 6.96e-34: 135: 17.49
+	Hs
		200185 TRAF4_HUMAN (17-498): 1.52e-94: 296: 29.12		TGFI1_HUMAN (71-397): 1.78e-33: 133: 17.43
+	Mm
		250818 TRAF6_MOUSE (2-498): 2.51e-110: 339: 27.87		FHL2_MOUSE (304-449): 1.31e-15: 79: 29.05
+	Mm
		936286 TRAF6_MOUSE (2-498): 2.51e-110: 339: 27.87		LIMD1_MOUSE (381-454): 4.13e-09: 60.6: 27.03
+	Hs
		1076580 TRAF6_HUMAN (2-498): 5.24e-109: 335: 27.08		TRIP6_HUMAN (396-457): 6.89e-09: 59.7: 27.42
+	Hs
		563794 TRAF4_HUMAN (17-498): 1.52e-94: 296: 29.12		ZNF3_HUMAN (79-288): 7.43e-19: 90.4: 6.45
+	Hs
		1199155 TRAF4_HUMAN (17-498): 1.52e-94: 296: 29.12		Q86U76_HUMAN (79-288): 5.93e-18: 87.3: 6.45
+	Hs
		549156 TRAF1_HUMAN (130-499): 1.15e-88: 279: 37.44		ZN250_HUMAN (362-457): 4.28e-23: 103: 6.25
+	Mm
		250822 TRAF4_MOUSE (17-498): 1.4e-92: 291: 28.92		FHL2_MOUSE (304-449): 1.31e-15: 79: 29.05
+	Hs
		1238810 TRI39_HUMAN (26-347): 3.57e-42: 159: 14.16		ZN383_HUMAN (52-421): 9.78e-60: 204: 9.45
+	Hs
		1293398 TRI39_HUMAN (26-347): 3.57e-42: 159: 14.16		PDLI5_HUMAN (1-282): 6.17e-28: 118: 24.82
+	Hs
		997546 TRI39_HUMAN (26-347): 3.57e-42: 159: 14.16		ZN543_HUMAN (80-290): 6.11e-13: 72.7: 4.13