HitPredict

Interactor 1: TRAF2 (Q12933)
TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3)
Gene: TRAF2

Interactor 2: SPHK1 (Q9NYA1)
Sphingosine kinase 1 (SK 1) (SPK 1) (EC 2.7.1.91) (Acetyltransferase SPHK1) (EC 2.3.1.-)
Gene: SPHK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.664

Property	Details
Experiments	25716317, 28521610, 11777919
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0051092 - positive regulation of NF-kappaB transcription factor activity
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 501 Hs			1 384
+	Hs
		1348332 TRAF6_HUMAN (2-498): 5.24e-109: 335: 27.08		SPHK1_HUMAN (1-379): 1.09e-133: 389: 100.00