HitPredict

Interactor 1: TRAF2 (Q12933)
TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3)
Gene: TRAF2

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.761

The method score is based on:

Property Details
Experiments 25416956, 16189514, 21516116, 28514442, 32296183, 33961781, 16260598, 36098982, 21903422, 9500555, 9718306, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, validated two hybrid, two hybrid prey pooling approach, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002637 - regulation of immunoglobulin production
GO:0002726 - positive regulation of T cell cytokine production
GO:0004842 - ubiquitin-protein transferase activity
GO:0005164 - tumor necrosis factor receptor binding
GO:0005737 - cytoplasm
and 18 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

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Last updated: 15 Jul 2024