HitPredict

Interactor 1: TRAF2 (Q12933)
TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3)
Gene: TRAF2

Interactor 2: TNR18 (Q9Y5U5)
Tumor necrosis factor receptor superfamily member 18 (Activation-inducible TNFR family receptor) (Glucocorticoid-induced TNFR-related protein) (CD antigen CD357)
Gene: TNFRSF18

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	10037686, 15944293
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 501 Hs			1 241
+	Hs
		639576 TRAF2_HUMAN (1-501): 2.31e-159: 463: 100.00		TNR5_HUMAN (34-224): 3.5e-48: 161: 17.86
+	Hs
		1021008 TRAF2_HUMAN (1-501): 2.31e-159: 463: 100.00		TNR11_HUMAN (28-190): 9.86e-44: 157: 25.15
+	Mm
		192583 TRAF2_MOUSE (1-501): 9.33e-158: 459: 86.83		TNR11_MOUSE (28-190): 1.46e-44: 159: 21.56
+	Hs
		989742 TRAF2_HUMAN (1-501): 2.31e-159: 463: 100.00		TNR9_HUMAN (34-226): 2.75e-42: 146: 25.23
+	Mm
		761824 TRAF2_MOUSE (1-501): 9.33e-158: 459: 86.83		TNR14_MOUSE (28-233): 2.48e-43: 149: 25.12
+	Hs
		738659 TRAF2_HUMAN (1-501): 2.31e-159: 463: 100.00		TNR3_HUMAN (34-214): 3.38e-39: 142: 18.95
+	Mm
		648951 TRAF2_MOUSE (1-501): 9.33e-158: 459: 86.83		TNR5_MOUSE (26-224): 9.98e-38: 135: 17.96
+	Hs
		591317 TRAF2_HUMAN (1-501): 2.31e-159: 463: 100.00		TNR1B_HUMAN (34-169): 2.17e-34: 129: 22.38
+	Mm
		591445 TRAF2_MOUSE (1-501): 9.33e-158: 459: 86.83		TNR9_MOUSE (34-222): 4.69e-37: 132: 24.88
+	Mm
		761805 TRAF2_MOUSE (1-501): 9.33e-158: 459: 86.83		TNR3_MOUSE (15-213): 2.59e-31: 120: 18.10
+	Hs
		796823 TRAF2_HUMAN (1-501): 2.31e-159: 463: 100.00		TNR4_HUMAN (35-167): 7.72e-28: 108: 23.72
+	Mm
		761804 TRAF2_MOUSE (1-501): 9.33e-158: 459: 86.83		TNR4_MOUSE (34-167): 7.45e-26: 103: 24.53
+	Hs
		1020846 TRAF2_HUMAN (1-501): 2.31e-159: 463: 100.00		TNR14_HUMAN (28-135): 4.69e-23: 96.4: 25.86
+	Hs
		436618 TRAF2_HUMAN (1-501): 2.31e-159: 463: 100.00		TNR16_HUMAN (28-157): 9.7e-10: 59.8: 15.04
+	Hs
		129532 TRAF5_HUMAN (7-501): 1.93e-115: 353: 30.90		TNR5_HUMAN (34-224): 3.5e-48: 161: 17.86
+	Rn
		78206 B5DFH7_RAT (1-501): 1.66e-151: 443: 86.43		TNR16_RAT (28-135): 6.42e-10: 60.5: 16.22
+	Hs
		129553 TRAF5_HUMAN (7-501): 1.93e-115: 353: 30.90		TNR9_HUMAN (34-226): 2.75e-42: 146: 25.23
+	Hs
		129536 TRAF5_HUMAN (7-501): 1.93e-115: 353: 30.90		TNR3_HUMAN (34-214): 3.38e-39: 142: 18.95
+	Hs
		129538 TRAF5_HUMAN (7-501): 1.93e-115: 353: 30.90		TNR4_HUMAN (35-167): 7.72e-28: 108: 23.72
+	Hs
		129526 TRAF5_HUMAN (7-501): 1.93e-115: 353: 30.90		TNR16_HUMAN (28-157): 9.7e-10: 59.8: 15.04