HitPredict

Interactor 1: DLG1 (Q12959)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)
Gene: DLG1

Interactor 2: KCJ12 (Q14500)
ATP-sensitive inward rectifier potassium channel 12 (Inward rectifier K(+) channel Kir2.2) (IRK-2) (Inward rectifier K(+) channel Kir2.2v) (Potassium channel, inwardly rectifying subfamily J member 12)
Gene: KCNJ12

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.692

Property	Details
Experiments	15024025, 14960569, 11181181, 24550280
Identification Methods	affinity chromatography technology, pull down, phage display
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 904 Hs			1 433
+	Hs
		80982 DLG1_HUMAN (1-904): 0: 725: 100.00		KCJ18_HUMAN (1-433): 0: 757: 98.61
+	Rn
		852397 DLG1_RAT (1-904): 0: 701: 92.54		KCJ12_RAT (1-433): 0: 726: 95.84
+	Hs
		929764 DLG1_HUMAN (1-904): 0: 725: 100.00		KCNJ2_HUMAN (6-433): 0: 686: 70.70
+	Rn
		1144015 DLG1_RAT (1-904): 0: 701: 92.54		KCNJ2_RAT (6-433): 0: 682: 70.93
+	Hs
		1054724 DLG3_HUMAN (139-904): 0: 585: 66.28		KCJ12_HUMAN (1-433): 0: 762: 100.00
+	Hs
		816147 DLG1_HUMAN (1-904): 0: 725: 100.00		KCNJ4_HUMAN (31-433): 0: 602: 63.58
+	Rn
		852399 DLG3_RAT (99-904): 0: 590: 64.57		KCJ12_RAT (1-433): 0: 726: 95.84
+	Hs
		816159 DLG1_HUMAN (1-904): 0: 725: 100.00		KCNJ6_HUMAN (40-381): 0: 527: 52.92
+	Hs
		1054729 PALS2_HUMAN (421-899): 2.36e-108: 346: 23.48		KCJ12_HUMAN (1-433): 0: 762: 100.00
+	Dm
		677699 DLG1_DROME (1-904): 0: 567: 48.67		Q8IGY2_DROME (18-364): 4.96e-175: 498: 49.01
+	Hs
		159210 CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64		KCJ12_HUMAN (1-433): 0: 762: 100.00
+	Hs
		942342 DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64		KCJ12_HUMAN (1-433): 0: 762: 100.00
+	Rn
		852398 CSKP_RAT (19-362): 1.15e-28: 125: 12.26		KCJ12_RAT (1-433): 0: 726: 95.84
+	Rn
		677769 DLG4_RAT (86-493): 2.93e-24: 111: 15.40		KCJ12_RAT (1-433): 0: 726: 95.84
+	Hs
		929762 DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64		KCNJ2_HUMAN (6-433): 0: 686: 70.70
+	Mm
		852403 DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07		KCNJ4_MOUSE (32-433): 0: 616: 63.64
+	Hs
		159173 CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64		KCNJ4_HUMAN (31-433): 0: 602: 63.58
+	Hs
		816146 DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64		KCNJ4_HUMAN (31-433): 0: 602: 63.58
+	Mm
		291382 DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07		KCNJ1_MOUSE (39-358): 1.54e-172: 489: 49.85
+	Mm
		1143532 DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07		KCJ10_MOUSE (42-354): 1.53e-159: 456: 44.76