HitPredict

Interactor 1: DLG1 (Q12959)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)
Gene: DLG1

Interactor 2: AGRA2 (Q96PE1)
Adhesion G protein-coupled receptor A2 (G-protein coupled receptor 124) (Tumor endothelial marker 5)
Gene: ADGRA2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	15021905, 24550280
Identification Methods	affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation, phage display
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 904 Hs			1 1338
+	Hs
		1021530 DLG1_HUMAN (1-904): 0: 725: 100.00		AGRA3_HUMAN (46-1338): 0: 644: 41.50
+	Hs
		1021524 DLG1_HUMAN (1-904): 0: 725: 100.00		AGRA1_HUMAN (753-1338): 7.79e-140: 440: 37.92
+	Hs
		146753 DLG1_HUMAN (1-904): 0: 725: 100.00		AGRB1_HUMAN (345-1282): 3.29e-84: 305: 15.22
+	Mm
		936185 DLG3_MOUSE (99-904): 0: 589: 64.69		LRC4C_MOUSE (33-285): 5.08e-41: 163: 24.47
+	Mm
		1143372 DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07		AGRL3_MOUSE (389-1334): 3.89e-143: 476: 16.94
+	Mm
		1143417 DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07		AGRA1_MOUSE (754-1338): 3e-136: 431: 36.18
+	Mm
		1143383 DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07		AGRB3_MOUSE (321-1329): 4.23e-108: 377: 13.92
+	Mm
		1143371 DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07		AGRL1_MOUSE (337-1220): 2.33e-105: 368: 15.09
+	Mm
		1143345 DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07		Q6PHM3_MOUSE (754-1277): 8.57e-112: 367: 36.75
+	Mm
		1119800 DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07		Q52KJ6_MOUSE (859-1338): 7.13e-107: 348: 31.21
+	Hs
		146752 DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64		AGRB1_HUMAN (345-1282): 3.29e-84: 305: 15.22
+	Hs
		225263 DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64		AGRB2_HUMAN (305-1294): 3.04e-83: 302: 14.79
+	Mm
		1112552 DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07		AGRB1_MOUSE (345-1279): 2.59e-80: 293: 14.87
+	Mm
		1143430 DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07		AGRB2_MOUSE (305-1294): 2.36e-80: 293: 15.14
+	Mm
		471547 DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07		LRC4B_MOUSE (8-189): 4.53e-45: 176: 30.89
+	Mm
		1143410 DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07		LRC4C_MOUSE (33-285): 5.08e-41: 163: 24.47
+	Mm
		1207544 DLG2_MOUSE (393-627): 3.09e-21: 101: 24.48		LRC4C_MOUSE (33-285): 5.08e-41: 163: 24.47
+	Hs
		1050029 SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49		LRIG1_HUMAN (71-193): 2.58e-20: 99: 27.64
+	Mm
		1143524 DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07		LGI1_MOUSE (79-239): 1.16e-14: 80.9: 29.19
+	Hs
		328209 DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64		LGI1_HUMAN (79-239): 9.12e-15: 80.9: 29.19