HitPredict

Interactor 1: DLG1 (Q12959)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)
Gene: DLG1

Interactor 2: LIN7C (Q9NUP9)
Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)
Gene: LIN7C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.922

The method score is based on:

Property Details
Experiments 26186194, 28514442, 14960569, 33961781, 34349018
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Guanylate_kin~PDZ, L27~L27_1, PDZ~PDZ
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0005923 - bicellular tight junction
GO:0008092 - cytoskeletal protein binding
and 5 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 904
Hs

1 197
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024