Interactor 1: NPRL3 (Q12980)
GATOR1 complex protein NPRL3 (-14 gene protein) (Alpha-globin regulatory element-containing gene protein) (Nitrogen permease regulator 3-like protein) (Protein CGTHBA)
Gene: NPRL3

Interactor 2: WDR24 (Q96S15)
GATOR2 complex protein WDR24 (EC 2.3.2.27) (WD repeat-containing protein 24)
Gene: WDR24

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 0.60 0.718

The method score is based on:

Property Details
Experiments 23723238, 28199306, 25263562, 28199315, 35831510
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005765 - lysosomal membrane
GO:0034198 - cellular response to amino acid starvation
GO:1904262 - negative regulation of TORC1 signaling
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 569
Hs

1 790
+ Hs
+ Hs
+ Dm
+ Dm

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Last updated: 15 Jul 2024