HitPredict

Interactor 1: GRIK2 (Q13002)
Glutamate receptor ionotropic, kainate 2 (GluK2) (Excitatory amino acid receptor 4) (EAA4) (Glutamate receptor 6) (GluR-6) (GluR6)
Gene: GRIK2

Interactor 2: GRIP1 (Q9Y3R0)
Glutamate receptor-interacting protein 1 (GRIP-1)
Gene: GRIP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12597860
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0043204 - perikaryon
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 908 Hs			1 1128
+	Hs
		761215 GRIK1_HUMAN (14-854): 0: 874: 80.26		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Hs
		786768 GRIA3_HUMAN (8-863): 0: 764: 39.02		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Hs
		786717 GRIA1_HUMAN (15-854): 0: 763: 39.46		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Hs
		816229 GRIA4_HUMAN (12-887): 0: 756: 37.39		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Rn
		585193 GRIA3_RAT (8-863): 0: 761: 38.91		GRIP1_RAT (1-1128): 0: 640: 93.88
+	Rn
		585145 GRIA1_RAT (14-854): 0: 759: 39.54		GRIP1_RAT (1-1128): 0: 640: 93.88
+	Rn
		585198 GRIA3_RAT (8-863): 0: 761: 38.91		GRIP2_RAT (1-1105): 6.49e-159: 501: 56.63
+	Hs
		1021483 GRIK2_HUMAN (1-908): 0: 965: 100.00		DLG1_HUMAN (9-377): 2.52e-17: 89.7: 13.17
+	Hs
		1022366 GRIK2_HUMAN (1-908): 0: 965: 100.00		DLG3_HUMAN (803-1120): 7.46e-15: 81.7: 14.15
+	Hs
		942335 GRIK2_HUMAN (1-908): 0: 965: 100.00		DLG4_HUMAN (999-1126): 8.04e-15: 81.3: 20.74
+	Rn
		677766 GRIK2_RAT (1-908): 0: 961: 99.12		DLG4_RAT (999-1126): 7.26e-15: 81.7: 20.74
+	Mm
		761217 GRIK2_MOUSE (1-908): 0: 960: 99.01		DLG4_MOUSE (999-1126): 8.76e-15: 81.3: 20.74
+	Hs
		761199 GRIK1_HUMAN (14-854): 0: 874: 80.26		DLG4_HUMAN (999-1126): 8.04e-15: 81.3: 20.74
+	Hs
		786696 GRIA1_HUMAN (15-854): 0: 763: 39.46		DLG1_HUMAN (9-377): 2.52e-17: 89.7: 13.17
+	Hs
		786757 GRIA3_HUMAN (8-863): 0: 764: 39.02		DLG4_HUMAN (999-1126): 8.04e-15: 81.3: 20.74
+	Mm
		1143566 GRIA3_MOUSE (8-863): 0: 763: 39.02		DLG4_MOUSE (999-1126): 8.76e-15: 81.3: 20.74
+	Rn
		585151 GRIA1_RAT (14-854): 0: 759: 39.54		DLG1_RAT (9-377): 2.47e-15: 83.2: 13.98
+	Rn
		585138 GRIA1_RAT (14-854): 0: 759: 39.54		DLG4_RAT (999-1126): 7.26e-15: 81.7: 20.74
+	Mm
		1143565 GRIA4_MOUSE (12-887): 0: 758: 37.39		DLG4_MOUSE (999-1126): 8.76e-15: 81.3: 20.74
+	Mm
		620881 GRIA1_MOUSE (14-854): 0: 756: 39.54		DLG3_MOUSE (792-1120): 2.61e-15: 83.2: 13.99