HitPredict

Interactor 1: GRIK3 (Q13003)
Glutamate receptor ionotropic, kainate 3 (GluK3) (Excitatory amino acid receptor 5) (EAA5) (Glutamate receptor 7) (GluR-7) (GluR7)
Gene: GRIK3

Interactor 2: GRIK3 (Q13003)
Glutamate receptor ionotropic, kainate 3 (GluK3) (Excitatory amino acid receptor 5) (EAA5) (Glutamate receptor 7) (GluR-7) (GluR7)
Gene: GRIK3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.755

The method score is based on:

Property Details
Experiments 29058671, 20951142
Identification Methods pull down, x-ray crystallography
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANF_receptor~ANF_receptor, ANF_receptor~Lig_chan, ANF_receptor~Lig_chan-Glu_bd, Lig_chan~Lig_chan, Lig_chan~Lig_chan-Glu_bd, Lig_chan-Glu_bd~Lig_chan-Glu_bd
Common GO terms GO:0001640 - adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
GO:0004970 - glutamate-gated receptor activity
GO:0005886 - plasma membrane
GO:0007215 - glutamate receptor signaling pathway
GO:0007216 - G protein-coupled glutamate receptor signaling pathway
and 17 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024