HitPredict

Interactor 1: ECH1 (Q13011)
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (EC 5.3.3.-)
Gene: ECH1

Interactor 2: TRAF1 (Q13077)
TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)
Gene: TRAF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.666

Property	Details
Experiments	25416956, 25996949, 31515488
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 328 Hs			1 416
+	Hs
		267402 ECI2_HUMAN (45-319): 4.15e-76: 240: 20.73		TRAF1_HUMAN (1-416): 4.57e-172: 489: 100.00
+	Hs
		995511 ECHP_HUMAN (59-316): 2.25e-61: 209: 24.62		TRAF1_HUMAN (1-416): 4.57e-172: 489: 100.00
+	Hs
		671549 ECHM_HUMAN (27-322): 3.57e-91: 275: 24.66		TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98
+	Hs
		995510 ECHP_HUMAN (59-316): 2.25e-61: 209: 24.62		TRAF2_HUMAN (3-415): 4e-124: 370: 38.01
+	Dm
		1376523 Q9W5W8_DROME (27-328): 3.81e-87: 266: 48.19		Q9W3I9_DROME (2-415): 1.3e-94: 293: 17.59
+	Hs
		778345 ECHA_HUMAN (70-246): 5.11e-15: 77.8: 31.87		TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98
+	Hs
		1022484 ECH1_HUMAN (1-328): 2.81e-109: 322: 100.00		TRAF3_HUMAN (3-262): 9.64e-11: 65.3: 15.77