HitPredict

Interactor 1: RPB1 (G3MZY8)
DNA-directed RNA polymerase II subunit RPB1 (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)
Gene: POLR2A

Interactor 2: RPAB5 (Q32P78)
DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5) (DNA-directed RNA polymerase III subunit L)
Gene: POLR2L

Species: Bos taurus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	16769904
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001055 - RNA polymerase II activity GO:0005665 - RNA polymerase II, core complex GO:0008270 - zinc ion binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1970 Bt			1 67
+	Hs
		624853 RPB1_HUMAN (1-1611): 0: 1878: 100.00		RPAB5_HUMAN (1-67): 3.73e-35: 114: 100.00
+	Sp
		143457 RPB1_SCHPO (11-1575): 0: 1650: 53.72		RPAB5_SCHPO (1-67): 4.78e-33: 109: 71.64
+	Sc
		375277 RPB1_YEAST (11-1593): 0: 1608: 49.18		RPAB5_YEAST (1-67): 1.8e-30: 103: 72.06
+	Hs
		156014 RPC1_HUMAN (16-1484): 0: 1354: 33.09		RPAB5_HUMAN (1-67): 3.73e-35: 114: 100.00
+	Sc
		375578 RPC1_YEAST (11-1471): 0: 1359: 32.60		RPAB5_YEAST (1-67): 1.8e-30: 103: 72.06
+	Sc
		501320 RPA1_YEAST (11-1471): 0: 1137: 22.94		RPAB5_YEAST (1-67): 1.8e-30: 103: 72.06
+	Hv
		89545 D4GZX6_HALVD (12-946): 0: 1012: 36.61		D4GWX5_HALVD (1-62): 1e-23: 85.8: 41.27
+	Hv
		89546 D4GZX7_HALVD (1051-1468): 3.82e-64: 227: 29.59		D4GWX5_HALVD (1-62): 1e-23: 85.8: 41.27
+	At
		1125370 NRPE1_ARATH (770-1472): 5.87e-40: 165: 14.42		NRPBA_ARATH (1-67): 6.99e-34: 111: 80.60
+	Hs
		317101 RPA1_HUMAN (994-1476): 4.47e-38: 159: 17.03		RPAB5_HUMAN (1-67): 3.73e-35: 114: 100.00
+	At
		1228007 NRPD1_ARATH (1084-1515): 2.16e-31: 137: 16.99		NRPBA_ARATH (1-67): 6.99e-34: 111: 80.60