Interactor 1: CDC16 (Q13042)
Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6)
Gene: CDC16

Interactor 2: CDC26 (Q8NHZ8)
Anaphase-promoting complex subunit CDC26 (Anaphase-promoting complex subunit 12) (APC12) (Cell division cycle protein 26 homolog)
Gene: CDC26

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.986

The method score is based on:

Property Details
Experiments 21516116, 25723520, 33961781, 35271311, 19668213, 25416956, 26496610, 28514442, 32296183, 21988832, unassigned1304, 20360068, 31515488
Identification Methods two hybrid, affinity chromatography technology, pull down, x-ray crystallography, molecular sieving, circular dichroism, two hybrid prey pooling approach, two hybrid array, validated two hybrid, tandem affinity purification and 1 others

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Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANAPC_CDC26~TPR_12
Common GO terms GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005829 - cytosol
GO:0007049 - cell cycle
GO:0007346 - regulation of mitotic cell cycle
and 4 others

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Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 620
Hs

1 85
+ Hs
+ Hs
+ Hs
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+ Mm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024