HitPredict

Interactor 1: CDC16 (Q13042)
Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6)
Gene: CDC16

Interactor 2: MED12 (Q93074)
Mediator of RNA polymerase II transcription subunit 12 (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (Mediator complex subunit 12) (OPA-containing protein) (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Trinucleotide repeat-containing gene 11 protein)
Gene: MED12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0016567 - protein ubiquitination
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 620 Hs			1 2177
+	Hs
		1022960 CDC16_HUMAN (1-620): 1.68e-124: 382: 100.00		CBP_HUMAN (1582-2176): 2.69e-11: 71.5: 13.45
+	Hs
		175154 OGT1_HUMAN (371-616): 3.19e-26: 116: 16.67		DIDO1_HUMAN (1479-2099): 1.5e-18: 95.4: 10.74
+	Hs
		175053 OGT1_HUMAN (371-616): 3.19e-26: 116: 16.67		KMT2C_HUMAN (1619-2174): 8.59e-16: 86.5: 10.80
+	Hs
		175080 OGT1_HUMAN (371-616): 3.19e-26: 116: 16.67		CBP_HUMAN (1582-2176): 2.69e-11: 71.5: 13.45
+	Hs
		1270827 APC7_HUMAN (75-607): 2.88e-19: 93.7: 12.73		CBP_HUMAN (1582-2176): 2.69e-11: 71.5: 13.45
+	Hs
		672870 CDC27_HUMAN (4-194): 3.68e-15: 81: 17.80		CBP_HUMAN (1582-2176): 2.69e-11: 71.5: 13.45