HitPredict

Interactor 1: STK4 (Q13043)
Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]
Gene: STK4

Interactor 2: AMOT (Q4VCS5)
Angiomotin
Gene: AMOT

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30266805
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0035329 - hippo signaling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 487 Hs			1 1084
+	Hs
		522609 STK4_HUMAN (1-487): 7.89e-170: 489: 100.00		MYH7_HUMAN (250-667): 1.32e-15: 84.6: 9.81
+	Hs
		528369 STK4_HUMAN (1-487): 7.89e-170: 489: 100.00		MYH6_HUMAN (273-669): 1.82e-15: 83.8: 10.08
+	Hs
		1023137 STK4_HUMAN (1-487): 7.89e-170: 489: 100.00		MYH2_HUMAN (381-687): 3.92e-14: 79.5: 14.01
+	Hs
		522545 STK4_HUMAN (1-487): 7.89e-170: 489: 100.00		MYH1_HUMAN (381-687): 4.64e-14: 79.5: 13.69
+	Hs
		528408 STK4_HUMAN (1-487): 7.89e-170: 489: 100.00		MYH8_HUMAN (382-687): 3.82e-13: 76.4: 13.10
+	Hs
		1023138 STK4_HUMAN (1-487): 7.89e-170: 489: 100.00		MYH13_HUMAN (435-755): 4.65e-12: 72.7: 20.63
+	Hs
		610802 KAPCB_HUMAN (14-319): 8.38e-123: 364: 25.63		MYH4_HUMAN (350-812): 1.95e-39: 162: 15.92
+	Hs
		522610 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		MYH7_HUMAN (250-667): 1.32e-15: 84.6: 9.81
+	Hs
		528371 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		MYH6_HUMAN (273-669): 1.82e-15: 83.8: 10.08
+	Hs
		1027452 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		MYH2_HUMAN (381-687): 3.92e-14: 79.5: 14.01
+	Hs
		522546 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		MYH1_HUMAN (381-687): 4.64e-14: 79.5: 13.69
+	Hs
		528409 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		MYH8_HUMAN (382-687): 3.82e-13: 76.4: 13.10
+	Hs
		1027453 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		MYH13_HUMAN (435-755): 4.65e-12: 72.7: 20.63
+	Hs
		528359 KAPCB_HUMAN (14-319): 8.38e-123: 364: 25.63		MYH6_HUMAN (273-669): 1.82e-15: 83.8: 10.08
+	Hs
		568567 KAPCA_HUMAN (14-319): 7.68e-123: 364: 26.90		MYH9_HUMAN (51-655): 1.51e-14: 81.1: 9.31
+	Hs
		522538 KAPCB_HUMAN (14-319): 8.38e-123: 364: 25.63		MYH1_HUMAN (381-687): 4.64e-14: 79.5: 13.69
+	Hs
		610795 KAPCB_HUMAN (14-319): 8.38e-123: 364: 25.63		MYH2_HUMAN (381-687): 3.92e-14: 79.5: 14.01
+	Hs
		1051339 MARK2_HUMAN (6-486): 9.18e-123: 378: 20.68		DCTN1_HUMAN (510-863): 3.81e-09: 63.3: 14.85
+	Hs
		568568 KAPCA_HUMAN (14-319): 7.68e-123: 364: 26.90		MYH10_HUMAN (479-879): 3.84e-12: 73: 12.04
+	Hs
		725152 PAK2_HUMAN (8-300): 1.44e-118: 359: 40.26		MYH10_HUMAN (479-879): 3.84e-12: 73: 12.04