HitPredict

Interactor 1: STK4 (Q13043)
Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]
Gene: STK4

Interactor 2: MAP1S (Q66K74)
Microtubule-associated protein 1S (MAP-1S) (BPY2-interacting protein 1) (Microtubule-associated protein 8) (Variable charge Y chromosome 2-interacting protein 1) (VCY2-interacting protein 1) (VCY2IP-1) [Cleaved into: MAP1S heavy chain; MAP1S light chain]
Gene: MAP1S

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	24366813, 35271311, 24255178, 23455922
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006915 - apoptotic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 487 Hs			1 1059
+	Hs
		1027383 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		MAP1S_HUMAN (16-1059): 0: 627: 100.00
+	Hs
		807705 STK4_HUMAN (1-487): 7.89e-170: 489: 100.00		MAP1B_HUMAN (313-1059): 3.25e-37: 155: 16.80
+	Hs
		807708 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		MAP1B_HUMAN (313-1059): 3.25e-37: 155: 16.80
+	Hs
		1186099 AKT3_HUMAN (2-330): 8.44e-131: 389: 21.68		MICA3_HUMAN (468-1017): 1.27e-16: 87.8: 13.10
+	Hs
		979887 PAK2_HUMAN (8-300): 1.44e-118: 359: 40.26		IF4G1_HUMAN (484-981): 1.2e-09: 64.7: 12.94
+	Hs
		1356429 TNIK_HUMAN (8-309): 2.1e-73: 254: 44.80		PCLO_HUMAN (460-942): 3.57e-12: 73.5: 8.23
+	Hs
		257718 TNIK_HUMAN (8-309): 2.1e-73: 254: 44.80		ANR17_HUMAN (472-998): 4.9e-09: 63.1: 12.17