HitPredict

Interactor 1: STK4 (Q13043)
Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]
Gene: STK4

Interactor 2: RASF6 (Q6ZTQ3)
Ras association domain-containing protein 6
Gene: RASSF6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 26186194, 24366813, 28514442, 33961781, 35271311, 36736316, 20920251
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Mst1_SARAH~Nore1-SARAH, Nore1-SARAH~Pkinase
Common GO terms GO:0006915 - apoptotic process
GO:0007165 - signal transduction
GO:0043065 - positive regulation of apoptotic process
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 487
Hs

1 369
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Last updated: 15 Jul 2024