HitPredict

Interactor 1: STK4 (Q13043)
Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]
Gene: STK4

Interactor 2: TBA1C (Q9BQE3)
Tubulin alpha-1C chain (EC 3.6.5.-) (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain]
Gene: TUBA1C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	23386615
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 487 Hs			1 449
+	Hs
		933421 STK4_HUMAN (1-487): 7.89e-170: 489: 100.00		TBA4A_HUMAN (1-448): 0: 724: 96.21
+	Hs
		933777 STK4_HUMAN (1-487): 7.89e-170: 489: 100.00		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		1026217 PAK1_HUMAN (3-305): 1.66e-117: 357: 40.91		TBA1C_HUMAN (1-449): 0: 733: 100.00
+	Ce
		110168 GCK1_CAEEL (1-369): 1.94e-128: 389: 44.76		O18688_CAEEL (1-439): 0: 699: 87.70
+	Hs
		933187 PAK1_HUMAN (3-305): 1.66e-117: 357: 40.91		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		1026181 PAK1_HUMAN (3-305): 1.66e-117: 357: 40.91		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		1026178 PAK1_HUMAN (3-305): 1.66e-117: 357: 40.91		TBA3E_HUMAN (1-439): 0: 700: 96.13
+	Hs
		428176 PAK1_HUMAN (3-305): 1.66e-117: 357: 40.91		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		1026221 PAK1_HUMAN (3-305): 1.66e-117: 357: 40.91		TBB2B_HUMAN (1-440): 0: 697: 40.23
+	Hs
		933780 PAK1_HUMAN (3-305): 1.66e-117: 357: 40.91		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		1313691 TNIK_HUMAN (8-309): 2.1e-73: 254: 44.80		TBB2B_HUMAN (1-440): 0: 697: 40.23