HitPredict

Interactor 1: STK4 (Q13043)
Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]
Gene: STK4

Interactor 2: PHOCN (Q9Y3A3)
MOB-like protein phocein (2C4D) (Class II mMOB1) (Mob1 homolog 3) (Mob3) (Mps one binder kinase activator-like 3) (Preimplantation protein 3)
Gene: MOB4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24255178
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 487 Hs			1 225
+	Hs
		1023117 STK4_HUMAN (1-487): 7.89e-170: 489: 100.00		MOB1A_HUMAN (17-212): 4.06e-89: 263: 20.10
+	Hs
		1027459 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		PHOCN_HUMAN (1-225): 8.34e-111: 318: 100.00
+	Hs
		1023070 STK4_HUMAN (1-487): 7.89e-170: 489: 100.00		MOB1B_HUMAN (19-212): 8.58e-88: 259: 20.30
+	Hs
		1027394 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		MOB3B_HUMAN (20-212): 5.12e-91: 268: 20.40
+	Hs
		1027437 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		MOB1A_HUMAN (17-212): 4.06e-89: 263: 20.10
+	Hs
		1027391 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		MOB1B_HUMAN (19-212): 8.58e-88: 259: 20.30
+	Dm
		1178607 Q9VEN3_DROME (25-328): 3.51e-124: 378: 48.21		MOB4_DROME (1-225): 1.36e-105: 305: 80.00
+	Hs
		1377585 STK24_HUMAN (19-367): 1.13e-121: 364: 45.20		PHOCN_HUMAN (1-225): 8.34e-111: 318: 100.00
+	Hs
		131625 STK25_HUMAN (14-327): 8.86e-120: 359: 48.74		PHOCN_HUMAN (1-225): 8.34e-111: 318: 100.00
+	Hs
		1350187 STK26_HUMAN (25-390): 1.4e-119: 358: 43.82		PHOCN_HUMAN (1-225): 8.34e-111: 318: 100.00
+	Hs
		1350192 STK26_HUMAN (25-390): 1.4e-119: 358: 43.82		S4R3N1_HUMAN (14-225): 1.29e-103: 301: 97.64
+	Dm
		56110 A1ZBH7_DROME (15-390): 2.09e-118: 377: 38.60		MOB1_DROME (22-212): 2.97e-86: 256: 21.68
+	Hs
		1026924 PAK2_HUMAN (8-300): 1.44e-118: 359: 40.26		MOB3C_HUMAN (19-217): 1.08e-87: 259: 17.87
+	Hs
		1356420 TNIK_HUMAN (8-309): 2.1e-73: 254: 44.80		PHOCN_HUMAN (1-225): 8.34e-111: 318: 100.00
+	Mm
		949324 TNIK_MOUSE (8-309): 1.1e-73: 254: 44.80		PHOCN_MOUSE (1-225): 8.34e-111: 318: 100.00
+	Hs
		1233571 MINK1_HUMAN (10-336): 5.97e-73: 252: 42.32		PHOCN_HUMAN (1-225): 8.34e-111: 318: 100.00
+	Dm
		1178592 Q7KV89_DROME (17-337): 2.42e-72: 249: 42.27		MOB4_DROME (1-225): 1.36e-105: 305: 80.00
+	Hs
		1198329 MINK1_HUMAN (10-336): 5.97e-73: 252: 42.32		MOB3B_HUMAN (20-212): 5.12e-91: 268: 20.40
+	Hs
		1174260 MINK1_HUMAN (10-336): 5.97e-73: 252: 42.32		MOB3C_HUMAN (19-217): 1.08e-87: 259: 17.87
+	Dm
		1178598 HIPPO_DROME (430-486): 2.19e-11: 68.4: 54.39		MOB4_DROME (1-225): 1.36e-105: 305: 80.00