HitPredict

Interactor 1: TRI32 (Q13049)
E3 ubiquitin-protein ligase TRIM32 (EC 2.3.2.27) (72 kDa Tat-interacting protein) (RING-type E3 ubiquitin transferase TRIM32) (Tripartite motif-containing protein 32) (Zinc finger protein HT2A)
Gene: TRIM32

Interactor 2: UB2E2 (Q96LR5)
Ubiquitin-conjugating enzyme E2 E2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E2) (UbcH8) (Ubiquitin carrier protein E2) (Ubiquitin-protein ligase E2)
Gene: UBE2E2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.767

Property	Details
Experiments	31028095, 21143188
Identification Methods	pull down, two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0005634 - nucleus GO:0070534 - protein K63-linked ubiquitination GO:0070936 - protein K48-linked ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 653 Hs			1 201
+	Hs
		1023307 TRI32_HUMAN (1-653): 1.07e-169: 501: 100.00		UB2E3_HUMAN (1-201): 6.37e-85: 251: 79.71
+	Hs
		919715 TRI32_HUMAN (1-653): 1.07e-169: 501: 100.00		UB2D2_HUMAN (55-200): 2.8e-82: 242: 64.38
+	Hs
		849316 TRI32_HUMAN (1-653): 1.07e-169: 501: 100.00		UB2D1_HUMAN (55-200): 1.23e-81: 240: 61.64
+	Hs
		851808 TRI32_HUMAN (1-653): 1.07e-169: 501: 100.00		UB2E1_HUMAN (28-201): 6.5e-80: 238: 89.71
+	Hs
		895783 TRI32_HUMAN (1-653): 1.07e-169: 501: 100.00		UB2D3_HUMAN (55-200): 1.28e-80: 238: 63.70
+	Hs
		896429 TRI32_HUMAN (1-653): 1.07e-169: 501: 100.00		UBE2N_HUMAN (53-200): 2.86e-70: 212: 45.27
+	Hs
		1297370 TRI39_HUMAN (11-469): 1.78e-113: 352: 13.43		UB2E2_HUMAN (1-201): 6.02e-94: 274: 100.00
+	Hs
		1282350 TRI39_HUMAN (11-469): 1.78e-113: 352: 13.43		UB2E3_HUMAN (1-201): 6.37e-85: 251: 79.71
+	Hs
		1336390 TRI39_HUMAN (11-469): 1.78e-113: 352: 13.43		UB2D4_HUMAN (55-200): 9.37e-83: 243: 63.01
+	Hs
		919870 TRI39_HUMAN (11-469): 1.78e-113: 352: 13.43		UB2D2_HUMAN (55-200): 2.8e-82: 242: 64.38
+	Hs
		849453 TRI39_HUMAN (11-469): 1.78e-113: 352: 13.43		UB2D1_HUMAN (55-200): 1.23e-81: 240: 61.64
+	Hs
		851889 TRI39_HUMAN (11-469): 1.78e-113: 352: 13.43		UB2E1_HUMAN (28-201): 6.5e-80: 238: 89.71
+	Hs
		895921 TRI39_HUMAN (11-469): 1.78e-113: 352: 13.43		UB2D3_HUMAN (55-200): 1.28e-80: 238: 63.70
+	Hs
		584923 RO52_HUMAN (6-470): 1.76e-111: 345: 14.62		UB2D2_HUMAN (55-200): 2.8e-82: 242: 64.38
+	Hs
		584907 RO52_HUMAN (6-470): 1.76e-111: 345: 14.62		UB2D1_HUMAN (55-200): 1.23e-81: 240: 61.64
+	Hs
		584910 RO52_HUMAN (6-470): 1.76e-111: 345: 14.62		UB2E1_HUMAN (28-201): 6.5e-80: 238: 89.71
+	Hs
		584916 RO52_HUMAN (6-470): 1.76e-111: 345: 14.62		UB2D3_HUMAN (55-200): 1.28e-80: 238: 63.70
+	Hs
		262161 TRIM3_HUMAN (1-645): 1.53e-106: 340: 17.03		UB2D1_HUMAN (55-200): 1.23e-81: 240: 61.64
+	Hs
		896547 TRI39_HUMAN (11-469): 1.78e-113: 352: 13.43		UBE2N_HUMAN (53-200): 2.86e-70: 212: 45.27
+	Hs
		584918 RO52_HUMAN (6-470): 1.76e-111: 345: 14.62		UBE2N_HUMAN (53-200): 2.86e-70: 212: 45.27