HitPredict

Interactor 1: MKRN3 (Q13064)
Probable E3 ubiquitin-protein ligase makorin-3 (EC 2.3.2.27) (RING finger protein 63) (RING-type E3 ubiquitin transferase makorin-3) (Zinc finger protein 127)
Gene: MKRN3

Interactor 2: PABP2 (Q86U42)
Polyadenylate-binding protein 2 (PABP-2) (Poly(A)-binding protein 2) (Nuclear poly(A)-binding protein 1) (Poly(A)-binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1)
Gene: PABPN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32460013
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:1990904 - ribonucleoprotein complex
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 507 Hs			1 306
+	Hs
		516487 MKRN3_HUMAN (1-507): 0: 599: 100.00		PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33
+	Hs
		1023456 MKRN3_HUMAN (1-507): 0: 599: 100.00		PABP4_HUMAN (163-260): 1.04e-20: 94.2: 17.17
+	Hs
		1023561 MKRN3_HUMAN (1-507): 0: 599: 100.00		PABP3_HUMAN (59-260): 1.51e-19: 90.7: 11.82
+	Hs
		516728 MKRN1_HUMAN (95-507): 0: 539: 53.61		PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33
+	Hs
		1031488 MKRN1_HUMAN (95-507): 0: 539: 53.61		PABP4_HUMAN (163-260): 1.04e-20: 94.2: 17.17
+	Hs
		1199044 MKRN2_HUMAN (94-477): 1.96e-161: 465: 34.88		PABP2_HUMAN (96-306): 9.35e-43: 150: 100.00
+	Hs
		1132325 MKRN1_HUMAN (95-507): 0: 539: 53.61		CELF3_HUMAN (134-231): 4.8e-14: 74.1: 17.35
+	Hs
		62097 MKRN2_HUMAN (94-477): 1.96e-161: 465: 34.88		EPAB2_HUMAN (105-306): 4.93e-37: 135: 46.89
+	Hs
		516684 MKRN2_HUMAN (94-477): 1.96e-161: 465: 34.88		PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33
+	Hs
		1031454 MKRN2_HUMAN (94-477): 1.96e-161: 465: 34.88		PABP4_HUMAN (163-260): 1.04e-20: 94.2: 17.17
+	Sp
		145436 YQC1_SCHPO (97-245): 4.85e-29: 122: 18.12		PAB2_SCHPO (107-255): 3.12e-34: 124: 48.32
+	Hs
		789482 ZC3H3_HUMAN (85-220): 2.61e-22: 103: 14.71		RBM34_HUMAN (117-251): 1.51e-30: 121: 31.11
+	Hs
		853946 ZC3H8_HUMAN (57-180): 2.99e-20: 93: 14.73		NCBP2_HUMAN (142-298): 5.3e-33: 120: 15.82
+	Hs
		1031384 ZC3H3_HUMAN (85-220): 2.61e-22: 103: 14.71		PABP4_HUMAN (163-260): 1.04e-20: 94.2: 17.17
+	Hs
		1221460 ZC3H3_HUMAN (85-220): 2.61e-22: 103: 14.71		PABP3_HUMAN (59-260): 1.51e-19: 90.7: 11.82
+	Hs
		1221414 ZC3H3_HUMAN (85-220): 2.61e-22: 103: 14.71		ZCRB1_HUMAN (170-286): 1.58e-16: 78.7: 27.97
+	Hs
		1235059 ZC3H8_HUMAN (57-180): 2.99e-20: 93: 14.73		ZCRB1_HUMAN (170-286): 1.58e-16: 78.7: 27.97