HitPredict

Interactor 1: MKRN3 (Q13064)
Probable E3 ubiquitin-protein ligase makorin-3 (EC 2.3.2.27) (RING finger protein 63) (RING-type E3 ubiquitin transferase makorin-3) (Zinc finger protein 127)
Gene: MKRN3

Interactor 2: PABP3 (Q9H361)
Polyadenylate-binding protein 3 (PABP-3) (Poly(A)-binding protein 3) (Testis-specific poly(A)-binding protein)
Gene: PABPC3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33744966, 34143182
Identification Methods	pull down, enzymatic study, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:1990904 - ribonucleoprotein complex
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 507 Hs			1 631
+	Hs
		516487 MKRN3_HUMAN (1-507): 0: 599: 100.00		PABP1_HUMAN (1-631): 0: 573: 91.99
+	Hs
		1023456 MKRN3_HUMAN (1-507): 0: 599: 100.00		PABP4_HUMAN (1-630): 0: 531: 69.60
+	Hs
		516728 MKRN1_HUMAN (95-507): 0: 539: 53.61		PABP1_HUMAN (1-631): 0: 573: 91.99
+	Hs
		1031488 MKRN1_HUMAN (95-507): 0: 539: 53.61		PABP4_HUMAN (1-630): 0: 531: 69.60
+	Hs
		516684 MKRN2_HUMAN (94-477): 1.96e-161: 465: 34.88		PABP1_HUMAN (1-631): 0: 573: 91.99
+	Hs
		1031454 MKRN2_HUMAN (94-477): 1.96e-161: 465: 34.88		PABP4_HUMAN (1-630): 0: 531: 69.60
+	Dm
		597087 Q9VP20_DROME (98-450): 1.42e-123: 368: 36.84		PABP_DROME (10-619): 2.5e-146: 439: 53.77
+	Hs
		1288644 MKRN1_HUMAN (95-507): 0: 539: 53.61		PABP5_HUMAN (6-179): 8.16e-39: 149: 23.16
+	Hs
		1221460 ZC3H3_HUMAN (85-220): 2.61e-22: 103: 14.71		PABP3_HUMAN (1-631): 0: 565: 100.00
+	Hs
		1031384 ZC3H3_HUMAN (85-220): 2.61e-22: 103: 14.71		PABP4_HUMAN (1-630): 0: 531: 69.60
+	Hs
		1288624 MKRN2_HUMAN (94-477): 1.96e-161: 465: 34.88		PABP5_HUMAN (6-179): 8.16e-39: 149: 23.16