Interactor 1: BIRC1 (Q13075)
Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein)
Gene: NAIP

Interactor 2: NLRC4 (Q9NPP4)
NLR family CARD domain-containing protein 4 (CARD, LRR, and NACHT-containing protein) (CED-4-like protein Clan) (Caspase recruitment domain-containing protein 12) (Ice protease-activating factor) (Ipaf)
Gene: NLRC4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 15107016
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BIR~NACHT, NACHT~NACHT, NACHT~NLRC4_HD, NACHT~NOD2_WH, NLRC4_HD~NOD2_WH
Common GO terms GO:0002221 - pattern recognition receptor signaling pathway
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0006915 - apoptotic process
GO:0006954 - inflammatory response
and 9 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024