Interactor 1: TRAF1 (Q13077)
TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)
Gene: TRAF1
Interactor 2: RIPK1 (Q13546)
Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)
Gene: RIPK1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.86 | 0.60 | 0.722 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956, 32296183, 8612133, 19287455, unassigned1304 |
| Identification Methods | two hybrid, affinity chromatography technology, validated two hybrid, two hybrid prey pooling approach, two hybrid array, coimmunoprecipitation |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005829 - cytosol GO:0006915 - apoptotic process GO:0031625 - ubiquitin protein ligase binding GO:0033209 - tumor necrosis factor-mediated signaling pathway GO:0051092 - positive regulation of NF-kappaB transcription factor activity |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
