HitPredict

Interactor 1: TRAF1 (Q13077)
TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)
Gene: TRAF1

Interactor 2: TRADD (Q15628)
Tumor necrosis factor receptor type 1-associated DEATH domain protein (TNFR1-associated DEATH domain protein) (TNFRSF1A-associated via death domain)
Gene: TRADD

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.647

The method score is based on:

Property	Details
Experiments	8565075, 19287455, 18439848
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005164 - tumor necrosis factor receptor binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006915 - apoptotic process GO:0009898 - cytoplasmic side of plasma membrane and 2 others more... GO:0033209 - tumor necrosis factor-mediated signaling pathway GO:0051092 - positive regulation of NF-kappaB transcription factor activity
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	416
Hs

1	312

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024