HitPredict

Interactor 1: TRAF1 (Q13077)
TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)
Gene: TRAF1

Interactor 2: TCAM1 (Q8IUC6)
TIR domain-containing adapter molecule 1 (TICAM-1) (Proline-rich, vinculin and TIR domain-containing protein B) (Putative NF-kappa-B-activating protein 502H) (Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta) (MyD88-3) (TIR domain-containing adapter protein inducing IFN-beta)
Gene: TICAM1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.674

Property	Details
Experiments	16323247, 14982987, 19795416
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 416 Hs			1 712
+	Hs
		1020783 TRAF2_HUMAN (3-415): 4e-124: 370: 38.01		TCAM1_HUMAN (1-712): 0: 1002: 100.00
+	Hs
		1216111 TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98		TCAM1_HUMAN (1-712): 0: 1002: 100.00
+	Mm
		936244 TRAF6_MOUSE (15-414): 1.94e-101: 313: 22.51		TCAM1_MOUSE (5-712): 0: 981: 53.34
+	Hs
		129577 TRAF5_HUMAN (14-261): 1.36e-16: 83.8: 13.91		TCAM1_HUMAN (1-712): 0: 1002: 100.00
+	Hs
		1024705 TRAF3_HUMAN (3-262): 9.64e-11: 65.3: 15.77		TCAM1_HUMAN (1-712): 0: 1002: 100.00
+	Hs
		1216101 TRAF4_HUMAN (27-136): 3.55e-09: 60.3: 17.86		TCAM1_HUMAN (1-712): 0: 1002: 100.00
+	Mm
		1141416 TRAF3_MOUSE (1-262): 2.34e-12: 70.7: 16.37		TCAM1_MOUSE (5-712): 0: 981: 53.34
+	Hs
		1204730 TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98		TCAM2_HUMAN (394-545): 2.01e-70: 231: 33.33
+	Mm
		936248 TRAF6_MOUSE (15-414): 1.94e-101: 313: 22.51		TCAM2_MOUSE (367-552): 5.5e-72: 235: 31.58