Interactor 1: ACACA (Q13085)
Acetyl-CoA carboxylase 1 (ACC1) (EC 6.4.1.2) (Acetyl-Coenzyme A carboxylase alpha) (ACC-alpha)
Gene: ACACA

Interactor 2: MCCB (Q9HCC0)
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)
Gene: MCCC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 24981860
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ACC_central~Carboxyl_trans, Biotin_carb_C~Carboxyl_trans, Biotin_lipoyl~Carboxyl_trans, Carboxyl_trans~Carboxyl_trans
Common GO terms GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005829 - cytosol
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 2346
Hs

1 563
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Pa
+ Sc
+ Hs
+ Hs
+ Ec
+ Ec
+ Nv

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024