Interactor 1: CSN1 (Q13098)
COP9 signalosome complex subunit 1 (SGN1) (Signalosome subunit 1) (G protein pathway suppressor 1) (GPS-1) (JAB1-containing signalosome subunit 1) (Protein MFH)
Gene: GPS1

Interactor 2: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 26186194, 28514442, 32034103, 31950832, 33961781, 19615732, 21145461, 16624822, 23926101, 22414063, 25043011, 20399188, 19444310, 18850735
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains JAB~PCI
Common GO terms GO:0000338 - protein deneddylation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 491
Hs

1 334
+ Mm
+ Mm
+ At
+ At
+ At
+ Ce
+ At
+ An
+ Ce
+ An
+ Hs
+ Dm
+ Hs
+ At
+ Hs
+ Hs
+ Dm
+ Sp
+ At
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024