Interactor 1: CSN1 (Q13098)
COP9 signalosome complex subunit 1 (SGN1) (Signalosome subunit 1) (G protein pathway suppressor 1) (GPS-1) (JAB1-containing signalosome subunit 1) (Protein MFH)
Gene: GPS1

Interactor 2: CSN8 (Q99627)
COP9 signalosome complex subunit 8 (SGN8) (Signalosome subunit 8) (COP9 homolog) (hCOP9) (JAB1-containing signalosome subunit 8)
Gene: COPS8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.977

The method score is based on:

Property Details
Experiments 28514442, 27173435, 9707402, 32034103, 33961781, 11337588, 22414063, 19141280, 12324474, 25043011, 19444310
Identification Methods affinity chromatography technology, biochemical, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CSN8_PSD8_EIF3K~PCI
Common GO terms GO:0000338 - protein deneddylation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 3 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 491
Hs

1 209
+ Mm
+ Mm
+ Hs
+ At
+ Mm

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Last updated: 15 Jul 2024