HitPredict

Interactor 1: ZBT17 (Q13105)
Zinc finger and BTB domain-containing protein 17 (Myc-interacting zinc finger protein 1) (Miz-1) (Zinc finger protein 151) (Zinc finger protein 60)
Gene: ZBTB17

Interactor 2: GFI1 (Q99684)
Zinc finger protein Gfi-1 (Growth factor independent protein 1) (Zinc finger protein 163)
Gene: GFI1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.747

The method score is based on:

Property Details
Experiments 19164764
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains zf-C2H2~zf-C2H2, zf-C2H2~zf-C2H2_4
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
GO:0046872 - metal ion binding
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 803
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024