HitPredict

Interactor 1: UBP4 (Q13107)
Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Ubiquitous nuclear protein homolog)
Gene: USP4

Interactor 2: UBP4 (Q13107)
Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Ubiquitous nuclear protein homolog)
Gene: USP4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.892

The method score is based on:

Property Details
Experiments 26455393, 37039823, 22001210, 22706160
Identification Methods affinity chromatography technology, proximity labelling technology, pull down, molecular sieving, nuclear magnetic resonance
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DUSP~DUSP, DUSP~Ubiquitin_3, Ubiquitin_3~Ubiquitin_3, UCH~UCH
Common GO terms GO:0000244 - spliceosomal tri-snRNP complex assembly
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005764 - lysosome
and 10 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 963
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1 963
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024