HitPredict

Interactor 1: CAF1A (Q13111)
Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-I p150) (hp150)
Gene: CHAF1A

Interactor 2: SETB1 (Q15047)
Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.366) (ERG-associated protein with SET domain) (ESET) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (Lysine N-methyltransferase 1E) (SET domain bifurcated 1)
Gene: SETDB1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	15327775, 19498464
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 956 Hs			1 1291
+	Mm
		103644 CAF1A_MOUSE (1-933): 1.43e-158: 491: 60.47		G5E8N3_MOUSE (1-1291): 0: 1333: 90.53
+	Hs
		1024523 CAF1A_HUMAN (1-956): 0: 589: 100.00		EHMT1_HUMAN (995-1287): 5.59e-70: 259: 21.27
+	Hs
		1024503 CAF1A_HUMAN (1-956): 0: 589: 100.00		EHMT2_HUMAN (999-1287): 2.75e-64: 241: 19.11
+	Hs
		1024469 CAF1A_HUMAN (1-956): 0: 589: 100.00		EZH2_HUMAN (1026-1272): 1.18e-48: 188: 13.13
+	Hs
		254514 ROCK2_HUMAN (143-739): 2.85e-24: 112: 10.98		SUV92_HUMAN (973-1290): 2.24e-67: 235: 20.98
+	Hs
		1080411 ITSN2_HUMAN (311-728): 3.08e-31: 134: 14.90		EZH2_HUMAN (1026-1272): 1.18e-48: 188: 13.13
+	Hs
		1080004 HYDIN_HUMAN (256-664): 3.79e-30: 131: 13.86		EZH2_HUMAN (1026-1272): 1.18e-48: 188: 13.13
+	Mm
		1149802 PLEC_MOUSE (21-811): 1.55e-09: 64.4: 10.08		Q6AXH7_MOUSE (1026-1272): 1.64e-48: 188: 13.13