HitPredict

Interactor 1: G3V617 (G3V617)
Mitogen-activated protein kinase 14 (EC 2.7.11.24) (Mitogen-activated protein kinase p38 alpha)
Gene: Mapk14

Interactor 2: ATF2 (Q00969)
Cyclic AMP-dependent transcription factor ATF-2 (cAMP-dependent transcription factor ATF-2) (Activating transcription factor 2) (cAMP response element-binding protein CRE-BP1)
Gene: ATF2

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	16407200
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0038066 - p38MAPK cascade
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 360 Rn			1 487
+	Hs
		547811 MK14_HUMAN (1-360): 1.84e-156: 445: 99.17		ATF2_HUMAN (1-477): 2.89e-150: 440: 98.53
+	Mm
		562973 MK14_MOUSE (1-360): 6.65e-157: 446: 99.72		ATF2_MOUSE (1-487): 9.65e-148: 432: 98.77
+	Hs
		547709 MK03_HUMAN (11-354): 1.78e-144: 415: 48.15		ATF2_HUMAN (1-477): 2.89e-150: 440: 98.53
+	Hs
		547805 MK11_HUMAN (1-348): 1.78e-144: 414: 75.86		ATF2_HUMAN (1-477): 2.89e-150: 440: 98.53
+	Hs
		547713 MK01_HUMAN (10-350): 1.48e-143: 412: 47.99		ATF2_HUMAN (1-477): 2.89e-150: 440: 98.53
+	Mm
		562985 MK11_MOUSE (1-350): 1.12e-145: 417: 76.29		ATF2_MOUSE (1-487): 9.65e-148: 432: 98.77
+	Hs
		173828 MK13_HUMAN (4-360): 5.58e-142: 408: 59.78		ATF2_HUMAN (1-477): 2.89e-150: 440: 98.53
+	Mm
		562980 MK03_MOUSE (14-350): 8.79e-144: 413: 48.55		ATF2_MOUSE (1-487): 9.65e-148: 432: 98.77
+	Mm
		562975 MK01_MOUSE (10-350): 1.01e-136: 394: 47.99		ATF2_MOUSE (1-487): 9.65e-148: 432: 98.77
+	Hs
		402080 MK14_HUMAN (1-360): 1.84e-156: 445: 99.17		JUN_HUMAN (113-411): 2.43e-50: 176: 17.48
+	Hs
		401456 MK03_HUMAN (11-354): 1.78e-144: 415: 48.15		JUN_HUMAN (113-411): 2.43e-50: 176: 17.48
+	Hs
		401473 MK01_HUMAN (10-350): 1.48e-143: 412: 47.99		JUN_HUMAN (113-411): 2.43e-50: 176: 17.48
+	Hs
		568066 MK01_HUMAN (10-350): 1.48e-143: 412: 47.99		JUND_HUMAN (134-410): 7.75e-37: 140: 16.85
+	Sp
		857024 HOG1_SCHPO (7-349): 2.03e-142: 409: 53.20		ATF1_SCHPO (138-422): 1.16e-35: 141: 22.73
+	Dm
		247434 MK38B_DROME (1-352): 5.87e-144: 413: 70.14		JRA_DROME (144-411): 3.18e-31: 123: 19.72
+	At
		1106531 MPK6_ARATH (3-351): 5.89e-140: 404: 45.48		BZP16_ARATH (123-390): 1.63e-32: 130: 13.43
+	Dm
		248406 MK38A_DROME (6-352): 1.18e-142: 410: 70.29		JRA_DROME (144-411): 3.18e-31: 123: 19.72
+	Dm
		576056 ERKA_DROME (2-349): 1.19e-136: 395: 48.45		JRA_DROME (144-411): 3.18e-31: 123: 19.72
+	Hs
		401593 MK09_HUMAN (8-348): 3.27e-114: 340: 50.14		JUN_HUMAN (113-411): 2.43e-50: 176: 17.48
+	Dm
		599211 ERKA_DROME (2-349): 1.19e-136: 395: 48.45		FOSLA_DROME (209-487): 6.76e-25: 110: 19.59