HitPredict

Interactor 1: TRAF3 (Q13114)
TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1) (RING-type E3 ubiquitin transferase TRAF3)
Gene: TRAF3

Interactor 2: TCAM1 (Q8IUC6)
TIR domain-containing adapter molecule 1 (TICAM-1) (Proline-rich, vinculin and TIR domain-containing protein B) (Putative NF-kappa-B-activating protein 502H) (Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta) (MyD88-3) (TIR domain-containing adapter protein inducing IFN-beta)
Gene: TICAM1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.741

The method score is based on:

Property Details
Experiments 28747347, 14982987, 31511519, 24577058, 16306936, 17327220, 18450748, 20418377
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002224 - toll-like receptor signaling pathway
GO:0005739 - mitochondrion
GO:0005768 - endosome
GO:0005829 - cytosol
GO:0010008 - endosome membrane
and 5 others

more...
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 568
Hs

1 712
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024