HitPredict

Interactor 1: TRAF3 (Q13114)
TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1) (RING-type E3 ubiquitin transferase TRAF3)
Gene: TRAF3

Interactor 2: M3K14 (Q99558)
Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF-kappa-beta-inducing kinase) (HsNIK) (Serine/threonine-protein kinase NIK)
Gene: MAP3K14

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.764

The method score is based on:

Property Details
Experiments 33198776, 20348096, 9275204, 25246529, 28514442, 30833792, 32296183, 31980649, 33961781, 11278268, 32707033, 15208311, 15084608, 23543740, unassigned1304, unassigned2173, 14743216
Identification Methods affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation, validated two hybrid, two hybrid array, two hybrid prey pooling approach, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0051607 - defense response to virus
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 568
Hs

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Last updated: 15 Jul 2024