HitPredict

Interactor 1: REST (Q13127)
RE1-silencing transcription factor (Neural-restrictive silencer factor) (X2 box repressor)
Gene: REST

Interactor 2: NONO (Q15233)
Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit)
Gene: NONO

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27976729
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006355 - regulation of DNA-templated transcription GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1097 Hs			1 471
+	Hs
		516490 REST_HUMAN (1-1097): 0: 670: 100.00		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		613436 REST_HUMAN (1-1097): 0: 670: 100.00		SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92
+	Hs
		1025022 REST_HUMAN (1-1097): 0: 670: 100.00		ELAV1_HUMAN (68-205): 7.38e-47: 166: 27.82
+	Hs
		1204629 ZN761_HUMAN (107-388): 2.73e-111: 365: 24.18		RBM4B_HUMAN (75-182): 7.1e-09: 59.3: 35.71
+	Hs
		1251650 ZN420_HUMAN (764-1091): 5.23e-59: 217: 7.62		RBM4_HUMAN (75-182): 7.64e-09: 59.3: 35.71
+	Hs
		1239553 ZFP62_HUMAN (857-1091): 3.41e-42: 169: 7.66		RBM4_HUMAN (75-182): 7.64e-09: 59.3: 35.71
+	Hs
		1294637 ZN845_HUMAN (716-1090): 3.59e-40: 163: 5.87		RBM4B_HUMAN (75-182): 7.1e-09: 59.3: 35.71
+	Hs
		57948 ZN320_HUMAN (157-342): 6.07e-16: 84.3: 28.72		RBM4B_HUMAN (75-182): 7.1e-09: 59.3: 35.71