HitPredict

Interactor 1: AAPK1 (Q13131)
5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)
Gene: PRKAA1

Interactor 2: TP4A1 (Q93096)
Protein tyrosine phosphatase type IVA 1 (EC 3.1.3.48) (PTP(CAAXI)) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1)
Gene: PTP4A1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28675297
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DSPc~Pkinase
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 559 Hs			1 173
+	Hs
		1021788 AAPK1_HUMAN (1-559): 0: 595: 100.00		TP4A2_HUMAN (4-173): 2.63e-54: 171: 87.65
+	Hs
		1025149 AAPK1_HUMAN (1-559): 0: 595: 100.00		TENS2_HUMAN (4-168): 1.8e-42: 152: 12.09
+	Hs
		1025207 AAPK1_HUMAN (1-559): 0: 595: 100.00		DUS9_HUMAN (18-167): 7.35e-35: 127: 18.30
+	Hs
		1183148 MARK2_HUMAN (10-545): 5.04e-150: 451: 29.64		CC14A_HUMAN (14-169): 1.28e-36: 134: 24.39
+	Sc
		419939 SNF1_YEAST (23-475): 3.4e-141: 424: 38.62		CDC14_YEAST (11-159): 3.24e-37: 135: 24.24