HitPredict

Interactor 1: AAPK1 (Q13131)
5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)
Gene: PRKAA1

Interactor 2: AAKG3 (Q9UGI9)
5'-AMP-activated protein kinase subunit gamma-3 (AMPK gamma3) (AMPK subunit gamma-3)
Gene: PRKAG3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.903

The method score is based on:

Property Details
Experiments 28514442, 31900314, 33961781, 32707033
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AdenylateSensor~CBS
Common GO terms GO:0004679 - AMP-activated protein kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 4 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 559
Hs

1 489
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024