HitPredict

Interactor 1: LIPA1 (Q13136)
Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1)
Gene: PPFIA1

Interactor 2: LIPB2 (Q8ND30)
Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2)
Gene: PPFIBP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	9624153
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	SAM_1~SAM_1, SAM_1~SAM_2, SAM_2~SAM_2
Common GO terms	GO:0005829 - cytosol GO:0048786 - presynaptic active zone
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1202 Hs			1 876
+	Hs
		259651 LIPA2_HUMAN (35-1202): 3.45e-130: 431: 62.82		LIPB2_HUMAN (1-876): 1.36e-162: 498: 100.00
+	Hs
		1025311 LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00		LIPB1_HUMAN (1-875): 2.93e-95: 323: 40.56
+	Hs
		259650 LIPA2_HUMAN (35-1202): 3.45e-130: 431: 62.82		LIPB1_HUMAN (1-875): 2.93e-95: 323: 40.56
+	Dm
		65319 A8DYM0_DROME (860-1122): 3.71e-105: 360: 42.21		A8DYM0_DROME (173-856): 1.3e-95: 326: 23.07
+	Hs
		1202993 LIPB2_HUMAN (434-1149): 2.41e-95: 327: 18.61		LIPB1_HUMAN (1-875): 2.93e-95: 323: 40.56
+	Hs
		259642 LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00		LIPA2_HUMAN (62-564): 5.06e-11: 68.9: 12.03
+	Hs
		255242 LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00		LIPA3_HUMAN (51-424): 1.08e-10: 67.8: 13.60
+	Hs
		1025277 LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00		LIPA1_HUMAN (4-331): 5.55e-09: 62.4: 12.81
+	Dm
		1374287 Q9VU88_DROME (604-1148): 6.76e-85: 292: 22.95		Q9VU88_DROME (279-842): 7.16e-78: 268: 30.65
+	Hs
		259634 LIPA2_HUMAN (35-1202): 3.45e-130: 431: 62.82		LIPA2_HUMAN (62-564): 5.06e-11: 68.9: 12.03
+	Hs
		255231 LIPA2_HUMAN (35-1202): 3.45e-130: 431: 62.82		LIPA3_HUMAN (51-424): 1.08e-10: 67.8: 13.60
+	Hs
		1146483 KAZRN_HUMAN (426-1152): 1.57e-78: 277: 20.33		KAZRN_HUMAN (114-797): 6.64e-58: 214: 21.23
+	Dm
		65321 A8DYM0_DROME (860-1122): 3.71e-105: 360: 42.21		M9PCD4_DROME (51-474): 3.98e-12: 72.3: 12.26
+	Dm
		114427 Q9VU88_DROME (604-1148): 6.76e-85: 292: 22.95		M9PCD4_DROME (51-474): 3.98e-12: 72.3: 12.26
+	Hs
		522585 MYH7_HUMAN (153-902): 1.92e-36: 152: 13.40		MYH7_HUMAN (4-370): 5.57e-11: 68.9: 13.61
+	Hs
		528356 MYH6_HUMAN (1-705): 1.59e-30: 133: 11.65		MYH6_HUMAN (9-600): 2.54e-15: 83.2: 9.21
+	Hs
		502901 MYH6_HUMAN (1-705): 1.59e-30: 133: 11.65		MYH3_HUMAN (59-497): 2.44e-10: 66.9: 15.34
+	Hs
		1268126 MY18A_HUMAN (1-565): 4.66e-28: 125: 13.27		MRCKB_HUMAN (119-372): 2.07e-09: 63.8: 14.04