HitPredict

Interactor 1: CACO2 (Q13137)
Calcium-binding and coiled-coil domain-containing protein 2 (Antigen nuclear dot 52 kDa protein) (Nuclear domain 10 protein NDP52) (Nuclear domain 10 protein 52) (Nuclear dot protein 52)
Gene: CALCOCO2

Interactor 2: CYTSB (Q5M775)
Cytospin-B (Nuclear structure protein 5) (NSP5) (Sperm antigen HCMOGT-1) (Sperm antigen with calponin homology and coiled-coil domains 1)
Gene: SPECC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30309841, 33545068
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 446 Hs			1 1068
+	Hs
		725151 CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00		MYH10_HUMAN (120-977): 3.57e-39: 161: 10.29
+	Hs
		528370 CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00		MYH6_HUMAN (148-986): 1.44e-34: 146: 9.91
+	Sc
		689222 SP110_YEAST (140-350): 3.36e-12: 70.6: 18.27		SP110_YEAST (154-788): 1.09e-79: 282: 20.57
+	Hs
		1129119 MY18A_HUMAN (127-365): 3.21e-10: 64.8: 15.81		CYTSB_HUMAN (1-1068): 5.36e-72: 262: 100.00
+	Hs
		1051310 DCTN1_HUMAN (104-339): 7.78e-10: 63.2: 10.83		CYTSB_HUMAN (1-1068): 5.36e-72: 262: 100.00
+	Hs
		724805 CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00		MYH9_HUMAN (34-584): 1.32e-23: 110: 9.16
+	Hs
		1025566 CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00		MYO5C_HUMAN (47-496): 1.63e-12: 74.3: 10.21
+	Hs
		725097 MYH11_HUMAN (85-439): 1.1e-09: 62.8: 8.29		MYH10_HUMAN (120-977): 3.57e-39: 161: 10.29
+	Hs
		528356 MYH6_HUMAN (94-439): 7.55e-10: 63.6: 12.78		MYH6_HUMAN (148-986): 1.44e-34: 146: 9.91
+	Hs
		724943 MY18A_HUMAN (127-365): 3.21e-10: 64.8: 15.81		MYH9_HUMAN (34-584): 1.32e-23: 110: 9.16
+	Hs
		724698 EPS15_HUMAN (77-234): 4.48e-10: 64: 11.88		MYH9_HUMAN (34-584): 1.32e-23: 110: 9.16
+	Hs
		522585 MYH7_HUMAN (94-439): 1.46e-09: 62.4: 12.78		MYH7_HUMAN (1-526): 4.38e-18: 92.6: 8.26
+	Hs
		502901 MYH6_HUMAN (94-439): 7.55e-10: 63.6: 12.78		MYH3_HUMAN (453-992): 2.92e-15: 83.4: 10.89
+	Hs
		211632 MY18A_HUMAN (127-365): 3.21e-10: 64.8: 15.81		ACTN4_HUMAN (963-1066): 6.3e-15: 81.6: 41.91
+	Hs
		522657 MYH7_HUMAN (94-439): 1.46e-09: 62.4: 12.78		MYH4_HUMAN (2-423): 3.1e-15: 83.4: 9.93
+	Hs
		1186077 MY18A_HUMAN (127-365): 3.21e-10: 64.8: 15.81		MICA3_HUMAN (956-1067): 2.33e-14: 80.5: 38.05
+	Hs
		1268099 MY18A_HUMAN (127-365): 3.21e-10: 64.8: 15.81		MYO5C_HUMAN (47-496): 1.63e-12: 74.3: 10.21
+	Hs
		1148939 MY18A_HUMAN (127-365): 3.21e-10: 64.8: 15.81		CYTSA_HUMAN (1-389): 7.43e-11: 68.7: 7.36
+	Hs
		1051322 DCTN1_HUMAN (104-339): 7.78e-10: 63.2: 10.83		CYTSA_HUMAN (1-389): 7.43e-11: 68.7: 7.36
+	Sc
		630950 USO1_YEAST (140-356): 2.63e-09: 61.7: 19.46		USO1_YEAST (23-518): 4.9e-10: 66.2: 14.71