HitPredict

Interactor 1: CACO2 (Q13137)
Calcium-binding and coiled-coil domain-containing protein 2 (Antigen nuclear dot 52 kDa protein) (Nuclear domain 10 protein NDP52) (Nuclear domain 10 protein 52) (Nuclear dot protein 52)
Gene: CALCOCO2

Interactor 2: PPR18 (Q6NYC8)
Phostensin (Protein phosphatase 1 F-actin cytoskeleton-targeting subunit) (Protein phosphatase 1 regulatory subunit 18)
Gene: PPP1R18

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	25416956, 30309841
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005856 - cytoskeleton
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 446 Hs			1 613
+	Hs
		1157430 MY18A_HUMAN (127-365): 3.21e-10: 64.8: 15.81		PPR18_HUMAN (1-613): 8.33e-74: 249: 100.00
+	Hs
		1056882 TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87		MDC1_HUMAN (15-599): 3.32e-18: 91.2: 8.86
+	Hs
		1117441 MY18A_HUMAN (127-365): 3.21e-10: 64.8: 15.81		TPRN_HUMAN (206-554): 4.48e-28: 121: 19.95
+	Hs
		724854 MYH9_HUMAN (144-345): 7.94e-09: 60.2: 15.05		TPRN_HUMAN (206-554): 4.48e-28: 121: 19.95
+	Hs
		1051320 DCTN1_HUMAN (104-339): 7.78e-10: 63.2: 10.83		MAP1S_HUMAN (78-572): 4.1e-21: 100: 16.19
+	Dm
		116377 M9PI41_DROME (135-347): 2.2e-10: 65.2: 17.72		CPN_DROME (39-577): 2.27e-14: 78.5: 9.95
+	Hs
		166047 DCTN1_HUMAN (104-339): 7.78e-10: 63.2: 10.83		SYNJ2_HUMAN (225-574): 1.83e-10: 66.4: 13.78
+	Hs
		1051385 DCTN1_HUMAN (104-339): 7.78e-10: 63.2: 10.83		TITIN_HUMAN (39-550): 4.58e-09: 62: 10.17
+	Rn
		1126747 Q5JC29_RAT (77-225): 3.69e-09: 60.9: 9.93		SYNJ1_RAT (20-456): 1.34e-09: 63.5: 10.17