Interactor 1: EI2BE (Q13144)
Translation initiation factor eIF2B subunit epsilon (eIF2B GDP-GTP exchange factor subunit epsilon)
Gene: EIF2B5

Interactor 2: EI2BG (Q9NR50)
Translation initiation factor eIF2B subunit gamma (eIF2B GDP-GTP exchange factor subunit gamma)
Gene: EIF2B3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 0.60 0.619

The method score is based on:

Property Details
Experiments 10858531, 33961781
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002183 - cytoplasmic translational initiation
GO:0003743 - translation initiation factor activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 7 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 721
Hs

1 452
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+ Sp
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+ Dm
+ Sc
+ Ss
+ Hs
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+ At
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+ At
+ At
+ At
+ Dm
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+ Sp

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Last updated: 15 Jul 2024